PGD with Comprehensive Chromosomal Screening

June 13, 2012 | By: Wendy Schillings, MD, FACOG With PGD, embryos created by IVF can be tested for genetic abnormalities or chromosome abnormalities so that only those IVF embryos without defects are placed into the uterus.

Additionally, we can greatly reduce the odds of a couple having multiple pregnancies (twins or triplets). It arms clinicians with the knowledge that they are transferring the most chromosomally fit embryo, therefore precluding the need to transfer multiple, unscreened embryos in the hope that one will be healthy enough to create an ongoing pregnancy and a healthy baby.

 

Transcription:
Today I'm here to talk about a new technique, Pre-plantation Genetic Diagnosis, PGD, with comprehensive chromosomal screening. With this technique, we can test day-five and six embryos to see if they are chromosomally normal. It is important that they are chromosomally normal because most likely a chromosomally abnormal embryo will not make a baby. Therefore, when we test these embryos, we want to see that the embryos are either 46,XX—a normal girl, or 46,XY—a normal boy.

PGD with comprehensive chromosomal screening is a new technique that is being researched extensively. It is our hope that this will enable couples to have higher pregnancy rates with in-vitro fertilization, while lowing in multiple rates, lowering in miscarriage rates, and hopefully having healthier pregnancies. Thank you.